Fraser Hof

Scientist | Medicinal Chemistry, Supramolecular Chemistry

Role: Scientist

Site: CDL-Vancouver

Stream: Health

Fraser is the Canada Research Chair in Supramolecular and Medicinal Chemistry. His lab is working on developing protein-binding supramolecular host molecules with unique patterns of selectivity that can’t be achieved with antibodies and other naturally evolved recognition systems, and their development into useful biochemical reagents. They are also working on the development of drug-like small molecule inhibitors of certain proteins involved in the epigenetic programming of cancer cells, which they are exploring as novel therapeutics with the help of collaborators across Canada and the US.

Fraser received his B.Sc. in Chemistry from the University of Alberta in 1998. He got his Ph.D. in supramolecular chemistry at The Scripps Research Institute with Julius Rebek, Jr. He studied medicinal chemistry as a post-doctoral fellow with François Diederich at ETH-Zurich, and has been a professor at the University of Victoria since 2005. Fraser has an unhealthy obsession with the subtleties of molecular recognition in water. He is passionate about creating chemical tools that drive biology and medicine in new directions. Fraser takes his greatest pleasures from family, students, writing, strong coffee, and soccer.